产品简介
英文名称
Anti-MBNL3 Polyclonal Antibody
宿主
Rabbit
别名
CHCR,?MBLX39,?MBXL
稀释比例
WB 1:8000-12000. IHC 1:25-100.
蛋白分子量
32/38kDa
Gene ID
55796
保存
Store at -20°C. Avoid freeze / thaw cycles.
储存液
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法
Affinity purification
亚型
IgG
免疫原
A synthetic peptide of human MBNL3
亚细胞定位
Cytoplasm Nucleus
Swiss Prot
Q9NUK0
背景资料
Mediates pre-mRNA alternative splicing regulation. Acts either as activator or repressor of splicing on specific pre-mRNA targets. Inhibits cardiac troponin-T (TNNT2) pre-mRNA exon inclusion but induces insulin receptor (IR) pre-mRNA exon inclusion in muscle. Antagonizes the alternative splicing activity pattern of CELF proteins. May play a role in myotonic dystrophy pathophysiology (DM). Could inhibit terminal muscle differentiation, acting at approximately the time of myogenin induction.
Public Immunogen Range
5-55/354aa
克隆类型
Polyclonal Antibody
交叉反应
Human Mouse
应用
WB IHC
规格
50ul 100ul
备注：
以上数据均来自公开文献, Solarbio暂未进行独立验证, 仅供参考。
These protocols are for reference only. Solarbio does not independently validate these methods.
实验图
Western blot analysis with MBNL3 antibody diluted at 1:10000;Lane: A549
Immunohistochemistry?of?paraffin-embedded Human prostate cancer?with?MBNL3 antibody diluted at 1:40