HP monoclonal antibody, clone 2F4
产品名称: HP monoclonal antibody, clone 2F4
英文名称: HP monoclonal antibody, clone 2F4
产品编号: MAB0776
产品价格: null
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围:
亚诺法生技股份有限公司(Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against native HP.
- Immunogen:
- Native purified human HP.
- Host:
- Mouse
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Ammonium sulfate precipitation
- Concentration:
- 1 mg/mL
- Isotype:
- IgG1, kappa
- Storage Buffer:
- In HEPES, 150 mM NaCl (50% glycerol, 0.01% BSA, 0.03% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- Western Blot (1:2000)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Haptoglobin phenotypes in health and disorders.
Sadrzadeh SM, Bozorgmehr J.Am J Clin Pathol. 2004 Jun;121 Suppl:S97-104.
- 2.
- Haptoglobin: function and polymorphism.
Wassell J.Clin Lab. 2000;46(11-12):547-52.
- 3.
- Biological functions of haptoglobin--new pieces to an old puzzle.
Dobryszycka W.Eur J Clin Chem Clin Biochem. 1997 Sep;35(9):647-54.
- Entrez GeneID:
- 3240
- Gene Name:
- HP
- Gene Alias:
- BP,HP2-ALPHA-2,HPA1S,MGC111141
- Gene Description:
- haptoglobin
- Omim ID:
- 140100
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a preproprotein, which is processed to yield both alpha and beta chains, which subsequently combine as a tetramer to produce haptoglobin. Haptoglobin functions to bind free plasma hemoglobin, which allows degradative enzymes to gain access to the hemoglobin, while at the same time preventing loss of iron through the kidneys and protecting the kidneys from damage by hemoglobin. Mutations in this gene and/or its regulatory regions cause ahaptoglobinemia or hypohaptoglobinemia. This gene has also been linked to diabetic nephropathy, the incidence of coronary artery disease in type 1 diabetes, Crohn's disease, inflammatory disease behavior, primary sclerosing cholangitis, susceptibility to idiopathic Parkinson's disease, and a reduced incidence of Plasmodium falciparum malaria. A similar duplicated gene is located next to this gene on chromosome 16. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
- Other Designations:
- binding peptide,haptoglobin alpha(1S)-beta,haptoglobin alpha(2FS)-beta,haptoglobin, alpha polypeptide,haptoglobin, beta polypeptide
- Related Disease
- Abortion, Spontaneous
- Albuminuria
- alpha-Thalassemia
- Alzheimer Disease
- Alzheimer disease
- Anemia
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- Anemia, sickle cell
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- Asthma
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- Atherosclerosis
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- Breast Neoplasms
- Carcinoma, Squamous Cell
- Cardiovascular Diseases
- Carotid Artery Diseases
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